Liu, J.; Fang, X.; Liu, Z.; Li, R.; Yang, Y.; Sun, Y.; Zhao, Z.; Wu, C.*, Expansion Microscopy with Multifunctional Polymer Dots. Advanced Materials, 2021,33(25), 2007854.
Expansion microscopy (ExM) provides nanoscale resolution on conventional microscopes via physically enlarging specimens with swellable polyelectrolyte gels. However, challenges involving fluorophore degradation and dilution during sample expansion have yet to be overcome. Herein, sequential cellular targeting, gel anchoring, and high-fidelity